A 5-month-old entire female Staffordshire Bull Terrier was presented with an unusual lower eyelid-defect of the right eye. There was an abnormal thickening and inversion of the lateral aspect of the right lower eyelid. The affected area incorporated the conjunctiva and was covered with abnormally long hairs. The lateral half of the right lower eyelid margin was absent. There was an associated conjunctivitis and keratitis in the right eye. A diagnosis of a coloboma in association with a dermoid of the lower eyelid was made. The defect was repaired with the use of a modified sliding skin graft with an excellent result.