Title:
Canine cutaneous mast cell tumors
Author(s):
L. VAN EETVELDE, K. CHIERS, L. VAN BRANTEGEM
Abstract:
Canine cutaneous mast cell tumors (cMCT) are a commonly encountered neoplasia in small animalpractice. Ninety-six percent of the cMCT can be diagnosed with cytology. Because of the variatingbiological character, it’s difficult to establish a prognosis. Therefore, the prognosis is assessed withmultiple prognostic factors: tumor location, systemic complaints, metastases, histological and cytologicalgrading, proliferation markers, KIT-staining pattern, KIT-mutation and tumor free margins. Thetreatment of choice is based upon the results of these prognostic factors, the clinical stage and the tumorlocation. Possible treatments include surgery, radiotherapy, chemotherapy, electrochemotherapy,tyrosine kinase inhibitors, cryotherapy and intraregional therapy with deionized water.