Nine pygmy goats underwent surgical treatment for obstructive urolithiasis in a period ofsix months. In two cases, (second) revision surgery was necessary resulting in a total of twelveprocedures under general anesthesia. Different anesthetic protocols were applied: analgesia wasprovided by an opioid (12/12) combined with either benzodiazepine (10/12) or an alpha-2 agonist(2/12). Anesthesia was induced with propofol (10/12) or ketamine (2/12) and maintained withisoflurane (8/12) or sevoflurane (4/12) in oxygen in a semi-closed circle system with continuousmonitoring during anesthesia. Minor complications were mild bradycardia (4/12), hypotension(3/12), metabolic acidosis (1/12) and hypothermia (12/12). In four cases, epidural anesthesia wasperformed; in one of those four cases, severe complications developed (paralysis, 1/4). The goatwas euthanized later. Although urethral obstruction increases the risk of general anesthesia, theselection of an appropriate anesthetic protocol, adequate preoperative examination/ preparationand detailed monitoring throughout anesthesia reduced the incidence of severe complications inthis case series.