85 (6) pp 355

Title: 
Combined atypical primary hypoadrenocorticism and primary hypothyroidism in a dog
Author(s): 
B. VANMAL, V. MARTLÉ, D. BINST, P. SMETS, S. DAMINET, D. PAEPE
Abstract: 

A dog with combined atypical primary hypoadrenocorticism and primary hypothyroidismis described. The dog presented with waxing and waning, vague complaints since more than ayear and had been treated with several drugs without complete resolution of signs. Based onthe abnormalities on physical examination, blood examination and abdominal ultrasonography,atypical primary hypoadrenocorticism and primary hypothyroidism were diagnosed.Glucocorticoid supplementation was started and gradually tapered to maintenance rate becauseof polydipsia. Ten days later, levothyroxine supplementation was started at a very low dose andwas gradually increased based on serum total thyroxine concentrations. The dog rapidly improvedand recovered completely. Follow-up over a one-year period did not reveal new abnormalities.The presence of combined primary hypoadrenocorticism and primary hypothyroidism has beeninfrequently described in dogs and may resemble the Schmidt’s syndrome in humans.

Full text: 
pp 355-364