After a period of sneezing and conjunctivitis, a young female cat was presented with leftsided facialsubcutaneous swellings and ocular disease characterized by a hyperemic conjunctiva with protrusion ofthe third eyelid. In the oral cavity, swellings were present labial of the premolar teeth and in thepterygopalatine fossa. The left submandibular lymphnode was enlarged. The cat sneezed from time totime but there was no nasal discharge. The skin lesions had a distinctive yellow color. Cytology of affectedskin revealed pyogranulomatous inflammation with eosinophils. Only deep sampling of the skin containedrepresentative tissue for cytologic, histopathologic and mycologic examination. Aspergillus sectionfumigatus was diagnosed on morphologic aspects of the mycologic culture and the fungus was identifiedby molecular technology as Aspergillus viridinutans. The definite diagnosis was sino-orbital aspergillosiswith extensive subcutaneous invasion. Due to progressive disease despite therapy, the cat was euthanized.