Acute steroid responsive meningitis-arteritis (SRMA) is a common neurological disorder in young dogs.Typical clinical symptoms of the acute form of SRMA are neck pain, depression and fever. This case reportdescribes a 1.5-year-old Pointer with uncommon neurological deficits (unilateral multiple cranial nerve deficitsand Horner’s syndrome) and an exceptional necrosis of the tongue. This was believed to be part of the systemicvasculitis accompanying SRMA. The patient also developed tail necrosis and iatrogenic calcinosis cutis, whichcomplicated further treatment of the dog.