This paper describes a case of malignant catarrhal fever in a sow herd in Belgium caused byinfection with ovine herpesvirus-2 (OHV-2). The 11 affected sows had high fever and 10 of themdied within 3 days after the onset of clinical disease. The most prominent macroscopic lesion was ahemorrhagic to pseudo-membranous gastritis. Histopathology revealed severe infiltration andnecrosis of the gastric mucosa. Neither antimicrobial treatment nor injection with anti-inflammatorydrugs ameliorated the severity of the disease. As the sows and sheep were housed in the same buildingwith the possibility of having direct nose-to-nose contact, and as PCR testing showed that the virusfound in the sows was identical to that found in the sheep, it is very likely that the infection wastransmitted from the subclinically infected sheep to the sows. The present case showed that OHV-2infection should be included in the differential diagnosis when facing problems of fever followed bydeath, especially when pigs are housed in close contact with sheep.