Incubation of 107 colony forming units/ml of Staphylococcus pseudintermedius in an undiluted, a 1:2 anda 1:4 diluted aqueous 2% acetic acid and 2% boric acid solution resulted in inactivation of the bacteria within30, 60 and 120 minutes, respectively. This indicates that a combination of these acids might be useful for localtreatment of S. pseudintermedius infections. Further clinical studies are necessary, however, to confirm thesein vitro results.