78 (1) 49-52

Title: 
Mast cell leukemia in a dog
Author(s): 
H. DE BOSSCHERE, S. DELOOSE
Abstract: 

Cutaneous mast cell tumors are common in dogs, but systemic involvement is rare. In these rarecases, however, neoplastic mast cells can appear in large numbers in the peripheral blood, giving riseto mast cell leukemia or systemic mastocytosis. In both cases, the liver, spleen and bone marrow areoften infiltrated with mast cells. Mast cell leukemia originates in the bone marrow and is characterizedby a diffuse bone marrow infiltration with mast cells. The present case report describes the resultsof the blood cell count (CBC), serum biochemical panel, autopsy, histopathology andimmunohistology of a 14-year-old male Jack Russell terrier with mast cell leukemia without cutaneousinvolvement.

Full text: 
pp 49-52
Case report(s)