2012 - 81 (5)

Volume 81 (2012), nr. 5

81 (5) pp 308-311

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pp 308-311
Question and answer

81 (5) pp 303-307

Title: 
Dermatitis ten gevolge van Devriesea agamarum- en Nannizziopsis vriesii-infecties bij hagedissen
Author(s): 
T. HELLEBUYCK, A. MARTEL
Abstract: 
Article in Dutch, no abstract in English
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pp 303-307
Continuing professional development

81 (5) pp 298-302

Title: 
Intracranial oligodendroglioma with optic nerve infiltration in a Labrador retriever
Author(s): 
R. JEURING, K. VAN DRIESSCHE, L. BOSSELER, C. DE VRIES, A. VANHAESEBROUCK, I. GIELEN, A. OEVERMANN, K. CHIERS
Abstract: 
A seven-year-old neutered male Labrador retriever was presented with behavioral changes and reducedvision. Neurological examination revealed blindness of the left eye with a positive pupillary lightreflex and a decreased mental status. Blood and cerebrospinal fluid analyses showed no abnormalities.MRI revealed a deviant area located in the thalamic, hypothalamic and caudate nuclear regions. Invasionof the left optic nerve was also observed. The dog was euthanized after 38 days of palliative treatment.Necropsy showed a non-encapsulated extruding white lardaceous mass, with a diameter of 2 cm,in the white matter, located in the ventral thalamic region near the chiasma opticum, which extended alongthe left optic nerve. Histologically, neoplastic cells had a “fried egg” appearance. Immunolabelling forglial fibrillary acidic protein demonstrated the presence of numerous reactive astrocytes. The tumor wasdiagnosed as a low grade (II) intracranial oligodendroglioma with infiltration of the optic nerve.
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pp 298-302
Case report(s)

81 (5) pp 290-297

Title: 
The use of intra-articular anesthesia as a diagnostic tool in canine lameness
Author(s): 
D. VAN VYNCKT, Y. SAMOY, L. MOSSELMANS, G. VERHOEVEN, F. VERSCHOOTEN, B. VAN RYSSEN
Abstract: 
Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusiveclinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the sourceof lameness. After a description of the preparation, technique and puncture sites, an overview is givenof a series of patients admitted for different joint problems. Intra-articular anesthesia proved to beapplicable in any joint, provided that the clinician was experienced and the dog was under sedation.In 87% of the cases, intra-articular anesthesia was positive. Medial coronoid disease of the elbow jointwas the most frequent indication for intra-articular anesthesia.
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pp 290-297
Case report(s)

81 (5) pp 283-289

Title: 
Complications in the diagnosis of OCD and LPC of the elbow in a young Dogue de Bordeaux
Author(s): 
I.COMEYNE, E. COPPIETERS, I. GIELEN, B. VAN RYSSEN
Abstract: 
This case report concerns a 14-month-old Dogue de Bordeaux with osteochondritis dissecans (OCD)and fragmented coronoid process (FCP). As to breed and age, this is a very typical case of elbow dysplasia.However, the different steps that were required to come to a correct diagnosis made the case to be particular.The dog was presented with complaints of acute progressive lameness. Based on clinical and radiographicexamination, a presumptive diagnosis of bilateral FCP was made. No obvious primary lesionswere found during arthroscopy. Due to persistent lameness, computed tomography was performed, whichrevealed an OCD lesion in the right elbow and a fissure in the left elbow. Eventually, both elbows weretreated by means of a second arthroscopy, with good results. This case illustrates that arthroscopic inspectionof the elbow should always be done thoroughly, especially for the detection of OCD and fissures as bothlesions are sometimes difficult to be observed.
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pp 283-289
Case report(s)

81 (5) pp 274-282

Title: 
Embryo transfer in horses: essential to modern breeding
Author(s): 
L.T.M.VANDENBERGHE, J. GOVAERE, H.NELIS, M. HOOGEWIJS, P. DAELS, A.VAN SOOM
Abstract: 
Nowadays, a valuable competition mare can produce offspring without interrupting its sport careerwhich is made possible by a technique called embryo transfer. The valuable mare is inseminated and anembryo is flushed seven days later. The early embryo is then transferred to the uterus of a recipient marethat carries the pregnancy to term.In 50% of the cases, flushing of the donor mare results in an embryo. After transfer, an average of70% of the recipient mares become pregnant. These percentages are influenced by several factors relatedto both the donor and recipient mares.
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pp 274-282
Review(s)

81 (5) pp 266-273

Title: 
Antimicrobial resistance: a multifaceted phenomenon
Author(s): 
F. BOYEN, F. PASMANS, P. BUTAYE, F. HAESEBROUCK
Abstract: 
Antibiotics and chemotherapeutics with antibacterial activity are currently indispensable in veterinarymedicine. The emergence of antimicrobial resistance poses a threat to the health of both humans andanimals and to the animal food production as we know it today. The current review clarifies some basicterms and concepts with regard to antimicrobial resistance. Moreover, a summary is provided of howresistance can be determined and how the results of susceptibility testing should be interpreted.
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pp 266-273
Review(s)

81 (5) pp 255-265

Title: 
The use of antiviral drugs in veterinary medicine
Author(s): 
A. DE VLEESCHAUWER, D. LEFEBVRE, K. DE CLERCQ
Abstract: 
There is an increasing interest in the use of antiviral agents for the treatment of viral infections in animals.To date, the veterinary clinical use of antiviral drugs has mainly been limited to the application ofdrugs developed for humans in companion animals. However, the research and development of antiviraldrugs against specific animal viruses are ongoing. The interest in the use of antiviral drugs is also growingin livestock farming, where viral infections often have a high economic and social impact. The developmentof drugs for food-producing animals in particular requires thorough knowledge of thepharmacokinetics and (eco) toxicity, for determining maximum residue limits (MRLs) and withdrawalperiods. Experience gained from human medicine shows that the therapeutic efficacy of antiviral drugs maydecrease with the emergence of less sensitive (resistant) virus variants. Therefore, the development ofdrugs with a high barrier to antiviral resistance, and especially for mass application in veterinary medicine,is very important. There are only a few studies on the efficacy of (human) antiviral drugs against animalviruses, and clinical trials are usually limited to efficacy and toxicity. There is a lack of scientific data onthe dosage and risk of resistance development of antiviral products in animals. Control of viral diseasesby means of an antiviral therapy appears to be attractive for multiple reasons, but a lot of research is requiredto achieve an appropriate practical application. This article provides a brief introduction on the developmentof antiviral resistance, and gives an overview of the literature on antiviral treatment options forthe most common viral diseases in domestic animals, with specific attention to the available data on antiviralresistance development.
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pp 255-265
Review(s)