Theme

English

77 (1) 2-9

Title: 
Equine sarcoids - part 1: clinical presentation and epidemiology
Author(s): 
L. BOGAERT, A. MARTENS, P. DEPOORTER, F. GASTHUYS
Abstract: 
Equine sarcoids are the most common skin tumors in horses and other equids. In their pathogenesis, thebovine papillomavirus (BPV) plays a major role. Many clinical manifestations have been described, rangingfrom small single lesions to multiple aggressively growing masses. Histopathologically, it is consideredas a biphasic tumor with epidermal hyperplasia and subepidermal proliferation of transformed fibroblasts.The diagnosis can be made clinically, histopathologically and/or by detection of BPV DNA. Sarcoidscan appear on any part of the body, but they are mostly localized on the ventral abdomen, the paragenitalregion, head and limbs. Sarcoids occur independent of breed, coat color, sex or age, but they develop morecommonly in young adults and certain families and breeds are more vulnerable than others. Transmissionof BPV is supposed to happen from cattle to horse or from horse to horse, possibly via insects.
Full text: 
pp 2-9
Theme

77 (2) 75-80

Title: 
Honing in de wondzorg: mythe of wetenschap? Deel 2: klinische gevallen bij de hond (Dutch)
Author(s): 
H. DE ROOSTER, J. DECLERCQ
Abstract: 
Honey is believed to have several positive effects on wound healing. In this case report the clinical outcome ofthe use of honey dressings is described in several clinical cases of dogs with skin wounds. The findings confirmthat wounds treated with honey heal quickly, that bacterial contamination is well controlled, debridement is effectiveand that the dressings are well tolerated in all patients.
Full text: 
pp 75-80
Theme

77 (2) 68-74

Title: 
Honing in de wondzorg: mythe of wetenschap? Deel 1: literatuuroverzicht (Dutch)
Author(s): 
H. DE ROOSTER, J. DECLERCQ, M. VAN DEN BOGAERT
Abstract: 
Honey is one of the oldest medicines. Throughout history its use in wound management has been recorded inseveral cultures throughout the whole world. Up till now, in Western society nontraditional health care practiceshave been regarded with scepticism, viewing them at best as “useless, but not harmful”.The emergence of multi-drug resistant organisms and chemofobia, has created a resurgence of interest in thetherapeutic use of honey. Honey of several floral sources has been studied in vitro to elucidate the scientific basisfor its effectiveness. Clinically, honey is particularly suitable for treating patients with large infected wounds.Honey has antibacterial properties, it enhances wound healing and there is minimal eschar formation when honeyis used. In contrast to many conventional drugs, no important adverse effects have been reported.
Full text: 
pp 68-74
Theme

77 (2) 62-67

Title: 
prognosisEquine sarcoids – Part 2: current treatment modalities
Author(s): 
L. BOGAERT, A. MARTENS, P. DEPOORTER, F. GASTHUYS
Abstract: 
Treatment of sarcoids is often challenging, due to the variable clinical presentation of lesions and thefrequent local recurrences. In this article, both the surgical and the non-surgical treatment of equine sarcoidsare reviewed. It is generally accepted that the prognosis is worse if unsuccessful attempts have beenmade previously. Therefore, the best available treatment option should always be used at the first attemptof treatment. Different surgical approaches have been reported, including conventional excision, cryosurgeryand CO2 laser surgery. Success rates are high if a non-touch approach, wide surgical margins andgeneral anesthesia can be applied. Local chemotherapy is a valuable addition in the treatment of sarcoidsand can be combined with surgery. Radiotherapy is a very successful treatment, but safety precautionsprevent routine application. Local immunotherapy including Bacillus Calmette-Guérin vaccination andimiquimod cream are commonly applied treatments which induce rather effective tumour regression.
Full text: 
pp 62-67
Theme

77 (3) 148-152

Title: 
Complications in a dog with disc associated Wobbler syndrome
Author(s): 
S. DE DECKER, I. VAN SOENS, H. HAERS, M. TSHAMALA, T. WAELBERS, S. BHATTI, L. VAN HAM
Abstract: 
This case report describes the occurrence of a second episode of clinical signs of disc associated Wobblersyndrome almost 2 years following ventral decompressive surgery and a rather rare complication aftermyelographic examination in the same dog.
Full text: 
pp 148-152
Theme

77 (3) 139-147

Title: 
Diagnosis, treatment and prognosis of disc associated Wobbler syndrome in dogs
Author(s): 
S. DE DECKER, S. BHATTI, I. GIELEN, L. VAN HAM
Abstract: 
Disc associated Wobbler syndrome (DAWS) is the most prevalent and most typical Wobbler syndrome indogs. It is typically seen in the middle-aged Dobermann Pinscher. Caudal cervical spinal cord compressionis caused by protrusion of the annulus fibrosus of the intervertebral disc into the spinal canal, sometimes incombination with ligamentum flavum hypertrophy and malformed vertebrae. Clinical signs vary from neckpain to tetraplegia. The diagnosis is generally made using myelography. There is a lot of controversyconcerning the treatment of this disease. Many surgical techniques have been developed for it, but little isknown about the conservative treatment. Objective data about the prognosis of this disease is scarce.
Full text: 
pp 139-147
Theme

77 (3) 131-138

Title: 
Equine sarcoids - Part 3: association with bovine papillomavirus
Author(s): 
L. BOGAERT, A. MARTENS, P. DEPOORTER, F. GASTHUYS
Abstract: 
The genetic material of the bovine papillomavirus (BPV) can be detected in virtually all equine sarcoids.Eight different types have been described, all inducing benign proliferation of epithelium in cattle. BPV-1 and -2are less strictly species-specific and can induce equine sarcoids in horses. Historically, association betweenBPV and equine sarcoids has been demonstrated using inoculation studies and detection of BPV DNA and BPVgene expression. The BPV genome is composed of 6 early and 2 late genes, with E5 and E6 being the mostimportant transforming genes. Specific BPV-1 variants associated with equine sarcoids have been reported,suggesting circulation of the virus between horses. In horses, a non-productive BPV infection occurs, withonly transcription of early genes, responsible for genome maintenance, regulation of cell growth and celltransformation. There is no formation of new infectious virus particles as is the case in the natural host.
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pp 131-138
Theme

77 (4) 207-218

Title: 
De metabole adaptatiemechanismen bij hoogproductieve melkkoeien (Dutch)
Author(s): 
P. BOSSAERT, J. LEROY, S. COOLS, H. VAN LOO, A. DE KRUIF, G. OPSOMER
Abstract: 
Paper in Dutch
Full text: 
pp 207-218
Theme

77 (5) 282-290

Title: 
De pathogenese en kliniek van ketonemie en leververvetting bij hoogproductieve melkkoeien (Dutch)
Author(s): 
P. BOSSAERT, S. COOLS, H. VAN LOO, J. LEROY, A. DE KRUIF, G. OPSOMER
Abstract: 
Paper in Dutch
Full text: 
pp 282-290
Theme

77 (6) 363-375

Title: 
De behandeling en preventie van ketonemie en leververvetting bij hoogproductieve melkkoeien (Dutch)
Author(s): 
S. COOLS, P. BOSSAERT, H. VAN LOO, A. DE KRUIF, G. OPSOMER
Abstract: 
Paper in Dutch
Full text: 
pp 363-375
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