Retrospective Study

English

87 (2) pp76

Title: 
Spectrum of arthroscopic findings in 84 canine elbow joints diagnosed with medial compartment erosion
Author(s): 
E. COPPIETERS , E. DE BAKKER, B. BROECKX, Y. SAMOY, G. VERHOEVEN, E. VAN DER VEKENS, B. VAN RYSSEN
Abstract: 
Elbow dysplasia is an important cause of forelimb lameness in large breed dogs. The aim ofthis study was to report on the arthroscopic findings associated with medial compartment erosion(MCE) of the canine elbow joint. Retrospectively, records of 84 elbow joints from 66 dogsdiagnosed arthroscopically with MCE were retrieved from a medical records database (2008 -2012). The radiographic degree of osteoarthritis was determined. Arthroscopic images and videoswere evaluated in detail. In nine joints (10.7%), MCE was the only pathological finding (= group1). Group 2 (n = 50, 59.5%) consisted of elbows with MCE concomitant with medial coronoidprocess (MCP) pathology. In group 3 (n = 25 joints, 29.8%), MCE was diagnosed during a second-look arthroscopy in dogs presented with lameness after arthroscopic treatment for medialcoronoid disease. There was a significant age difference (p < 0.001) between the groups, with dogsin group 1 being the oldest. Complete erosion of the medial compartment was most commonlyfound in group 1, whereas focal cartilage erosion was mostly identified in group 2. Overall, additionalcartilage pathology of the lateral part of the humeral condyle and/or the radial head wasrecognized in 58.3% of the joints (49/84).
Full text: 
pp 076-085
Retrospective Study

87 (1) pp 22

Title: 
Presence of resistance against ‘highest priority critically important antimicrobials’ in Escherichia coli isolates from dogs and cats
Author(s): 
A. VAN CLEVEN, F. BOYEN, D. PAEPE, I. CHANTZIARAS, S. SARRAZIN, F. HAESEBROUCK, J. DEWULF
Abstract: 
A descriptive retrospective analysis of 811 antibiograms in dogs and cats was carried out in orderto get a better insight into the prevalence of antimicrobial resistance against ‘critically important antimicrobialswith highest priority for human medicine’ in dogs and cats. A veterinary diagnostic laboratoryperformed antimicrobial susceptibility testing on 811 Escherichia coli isolates obtained fromveterinary clinical samples from dogs and cats in Flanders, Belgium. These isolates were mainly fromfecal (62.5%) or urogenital (30.5%) origin. A disk diffusion method with breakpoints provided by thesupplier of the antibiotic disks was used for antimicrobial susceptibility testing. The results indicatedthat 9.5% of the Escherichia coli isolates were resistant against or intermediate susceptible to marbofloxacine,16.7% to enrofloxacine and 15.7% to cefovecin. The unexpected difference in resistancebetween marbofloxacine and enrofloxacin may be, at least partially, explained by the different clinicalbreakpoints used to interpret the results of sensitivity tests for dog and cat isolates in both agents. Theobserved resistance in this study might be related to the regular use of fluoroquinolones and third generationcephalosporins. Therefore, the use of ‘critically important antimicrobials with highest priorityfor human medicine’ remains an important issue in small animal veterinary medicine.
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pp 22-29
Retrospective Study

86 (5) pp 285-290

Title: 
Ultrasound-guided removal of vegetal foreign bodies in lower extremities of dogs: a retrospective study of 19 cases
Author(s): 
E. FAUCHON, C. LASSAIGNE, G. RAGETLY, E. GOMES
Abstract: 
Subcutaneous abscesses or granulomas in the lower extremities of dogs commonly occursecondary to the penetration and migration of vegetal foreign bodies (FBs). The aim of thisstudy was to describe the clinical presentation and ultrasonographic appearance of intact grassawn FBs in the lower extremities of dogs, and their ultrasound-guided retrieval with particularemphasis on the feasibility, effectiveness and prognosis associated with this technique. In thisretrospective study, 22 FBs were identified ultrasonographically in 19 dogs. The procedureresulted in the successful retrieval of the FB in 100% of dogs, and the clinical signs resolved in90% (n=17) in less than ten days. No complications or recurrence were encountered. This studyshows that ultrasonographic examination should be the first-choice modality when a vegetal FBis suspected within the distal extremity, as it allows both identification and removal of the FBwith a minimally invasive procedure, with short- and long-term effectiveness and good prognosis.
Full text: 
pp 285-290
Retrospective Study

86 (1) pp 24

Title: 
Sole prednisolone therapy in canine meningoencephalitis of unknown etiology
Author(s): 
I. CORNELIS, L. VAN HAM, S. DE DECKER, K. KROMHOUT, K. GOETHALS, I. GIELEN, S. BHATTI
Abstract: 
Meningoencephalitis of unknown etiology (MUE) is a frequently diagnosed and often fataldisease in veterinary neurology. The aim of this retrospective study was to assess the efficacy ofthree different sole prednisolone treatment schedules in dogs diagnosed with MUE. The dogswere diagnosed clinically with MUE based on previously described inclusion criteria, and treatedwith a three-, eight- or eighteen-week-tapering prednisolone schedule. Thirty eight dogs were includedin the study. Seventeen, fifteen and six dogs received the three-, eight- and eighteen-weektapering schedule, respectively. Overall, 37% of the dogs died or were euthanized because ofMUE, and a significant difference in survival time was seen between the three treatment schedules.Surprisingly, the highest number of dogs that died because of MUE was seen in the eightweektreatment schedule (56%), followed by the three-week (26%) and eighteen-week (0%)treatment schedule. Based on the results of this study, no definitive conclusions can be drawnregarding the ideal prednisolone dosing protocol for dogs diagnosed with MUE. However, a moreaggressive and immunosuppressive treatment protocol might lead to a better outcome.
Full text: 
pp 24-28
Retrospective Study

85 (5) pp275

Title: 
Treatment of multicentric or cranial mediastinal high-grade T-cell lymphoma in dogs with a first-line CCNU-L(-chlorambucil)-CHOP protocol
Author(s): 
M. OSSOWSKA, E. TESKE, L. BEIRENS-VAN KUIJK, M. ZANDVLIET, J.P. DE VOS
Abstract: 
This retrospective study determined disease free survival (DFS) and progression freesurvival (PFS) in chemo-naïve dogs with multicentric or cranial mediastinal high-grade T-celllymphoma, treated with a first-line CCNU-L(-chlorambucil)-CHOP protocol. Of thirteen dogswith multicentric lymphoma, 92.3% achieved a complete remission (CR), and the median DFSand PFS was 317 and 256 days, respectively. Three dogs had cranial mediastinal lymphoma,and achieved a CR with a median DFS and PFS of 978 and 1007 days, respectively. The oneandtwo-year DFS/PFS probability estimate for dogs with multicentric lymphoma was 0.50/0.46and 0.42/0.38, respectively, for dogs with cranial mediastinal lymphoma 0.67/0.67. Neutropeniaand thrombocytopenia were reported in 52.9% and 50% of the dogs, respectively, while 56.3%experienced grade 1-4 nephrotoxicity, hypothesized to be lomustine-induced. It was concludedthat, compared to historical data, the currently described first-line CCNU-L(-chlorambucil)-CHOP protocol could benefit the survival of dogs with multicentric or cranial mediastinal highgradeT-cell lymphoma.
Full text: 
pp 275-284
Retrospective Study